Goserelin: The Hormone Therapy for Prostate and Breast Cancer
What is Goserelin?
Goserelin is a gonadotropin-releasing hormone (GnRH) agonist used in the treatment of breast cancer, prostate cancer, endometriosis, and abnormal uterine bleeding. It works by suppressing the production of sex hormones like testosterone and estrogen.
How Goserelin Works
Goserelin works by blocking the secretion of hormones that promote the growth of certain cancers. By reducing estrogen in women and testosterone in men, it helps shrink cancerous tumors. In locally advanced breast cancers it is generally used in combination of Flutamide.
When to Use Goserelin
● Prostate Cancer: Reduces testosterone to slow down cancer cell growth.
● Breast Cancer: Reduces estrogen levels to prevent cancer cell growth in estrogen receptor-positive breast cancer.
● Endometriosis: Reduces estrogen to relieve symptoms of endometriosis.
Dosage
● Adult Dose: 3.6 mg or 10.8 mg given as a subcutaneous injection once a month or every 3 months.
● Pediatric Dose: As its safety profile in children is not available it is not generally recommended for children under 18 years.
Side Effects
● Hot flashes, headaches, reduced libido, bone thinning, and mood swings.
Common Brands in India: Zoladex, Goselin
FAQ
Does Goserelin cause weight gain?
Weight gain is a possible side effect, but it is not very common.
How long is Goserelin treatment?
Treatment duration depends on the specific condition being treated. It can range from a few months to several years.
Can Goserelin be used in women with breast cancer?
Yes, it is used in pre-menopausal women with estrogen receptor-positive breast cancer to lower estrogen levels.
Disclaimer
Goserelin should be administered under medical supervision. HealthPil connects you with oncologists for personalized treatment plans.