Ramipril: The ACE Inhibitor for Hypertension and Heart Failure
What is Ramipril?
Ramipril is an ACE inhibitor (Angiotensin-Converting Enzyme Inhibitor) used to treat high blood pressure (hypertension), heart failure, and to reduce the risk of heart attack or stroke in patients with cardiovascular risk.
How Ramipril Works
Ramipril inhibits the enzyme ACE, which converts angiotensin I to angiotensin II, a potent vasoconstrictor. By blocking this enzyme, Ramipril helps to relax blood vessels, lower blood pressure, and reduce the workload on the heart.
When to Use Ramipril
● Hypertension: Ramipril is used to lower high blood pressure and reduce the risk of stroke, heart attack, and kidney damage.
● Heart Failure: It is used to manage heart failure and improve heart function.
● Post-Myocardial Infarction: Ramipril is prescribed after a heart attack to reduce the risk of complications.
Dosage
● Adult Dose for Hypertension: The typical starting dose is 2.5 mg once daily, which can be increased based on blood pressure levels.
● Adult Dose for Heart Failure: The usual dose is 5 mg once daily, with possible increases.
Side Effects
● Common Effects: Cough, dizziness, headache, and high potassium levels.
● Serious Adverse Effects: Angioedema (swelling of deeper skin layers), low blood pressure, and kidney dysfunction.
Common brands: Cardace, Ramistar.