Raloxifene: The Selective Estrogen Receptor Modulator for Osteoporosis
What is Raloxifene?
Raloxifene is a selective estrogen receptor modulator (SERM) used to prevent and treat osteoporosis in postmenopausal women and to reduce the risk of breast cancer in high-risk women.
How Raloxifene Works
Raloxifene binds to estrogen receptors, mimicking the effects of estrogen in some tissues (such as bones) and blocking its effects in others (such as the breast and uterus). It helps maintain bone density and reduces the risk of fractures.
When to Use Raloxifene
● Osteoporosis: Raloxifene is used to prevent and treat osteoporosis in postmenopausal women, improving bone strength.
● Breast Cancer Risk Reduction: It is used to reduce the risk of breast cancer in women at high risk.
Dosage
● Adult Dose for Osteoporosis: Typically, 60 mg once daily.
● Adult Dose for Breast Cancer Prevention: Typically, 60 mg once daily.
Side Effects
● Common Effects: Hot flashes, leg cramps, and joint pain.
● Serious Adverse Effects: Blood clots, stroke, and liver disease.
Common brands: Bonmax, Ralista.