Naltrexone: The Medication for Addiction and Alcoholism
What is Naltrexone?
Naltrexone is an opioid antagonist used to treat opioid and alcohol dependence. It blocks the effects of opioids and reducing the desire to drink alcohol. Naltrexone is often part of a comprehensive addiction treatment plan, which may include counseling and other medications.
How Naltrexone Works
Naltrexone binds to the opioid receptors in the brain without activating them. This prevents the feeling of euphoria or “high” that opioids cause. It also reduces alcohol cravings by affecting dopamine release in the brain, which causes pleasure and addiction.
When to Use Naltrexone
● Opioid Addiction: Naltrexone helps in preventing relapses in people recovering from opioid addiction, helping reduce cravings and the risk of misuse.
● Alcohol Use Disorder: Naltrexone is also prescribed to help reduce cravings and limit alcohol consumption.
Dosage
●Adult Dose for Alcohol Dependence: 50 mg once daily.
● Adult Dose for Opioid Dependence: 50 mg daily, typically after detoxification and withdrawal symptoms have been managed.
Side Effects
● Common Effects: Nausea, headache, dizziness, and fatigue.
● Serious Adverse Effects: Liver damage, severe allergic reactions, and depression. It can also lead to opioid withdrawal symptoms in individuals who have opioids in their system.
Common brands: Naltima, Nodict.
