Hydralazine: The Vasodilator for Hypertension and Heart Failure
What is Hydralazine?
Hydralazine is a direct-acting vasodilator used to treat moderate to severe hypertension (high blood pressure) and heart failure. It works by relaxing the blood vessel walls allowing blood to flow more easily and effortlessly to vital organs and tissues and reducing the strain on the heart.
How Hydralazine Works
Hydralazine works by directly relaxing the smooth muscles in the blood vessels, leading to vasodilation (widening of the blood vessels), which helps to reduce blood pressure and decrease heart workload.
When to Use Hydralazine
● Hypertension: For controlling high blood pressure, especially when other medications are ineffective.
● Heart Failure: Often used in combination with other medications to reduce heart failure symptoms.
Dosage
● Adult Dose: 25 mg 3-4 times daily, increasing as needed. Usual dosage range is 100-200mg/day. Maximum dose of 300 mg/day.
● Pediatric Dose: 0.1-0.5 mg/kg/dose every 6- 8 hourly for children with severe hypertension. Maximum dose is 2 mg/kg/dose.
Side Effects
● Dizziness, headache, tachycardia, fluid retention, and lupus-like symptoms.
Common Brands in India: Hydralaze, Hydralazine.
FAQ
Can Hydralazine be used for stroke prevention?
While Hydralazine is primarily used for hypertension, it may help reduce stroke risk by controlling blood pressure.
Does Hydralazine cause fluid retention?
Yes, fluid retention is a possible side effect, especially with long-term use.
Can Hydralazine be taken with other blood pressure medications?
Yes, it is often used in combination with diuretics and beta-blockers for effective hypertension control.
Disclaimer
Hydralazine should be used under medical supervision due to potential side effects. HealthPil connects you with cardiologists for optimal heart and blood pressure management.