Sofosbuvir: A Revolutionary Treatment for Hepatitis C
Sofosbuvir is an antiviral used in the treatment of chronic hepatitis C monoinfection or HCV/HIV coinfection. It works by inhibiting the replication of the hepatitis C virus (HCV) in the body.
What is Sofosbuvir?
Sofosbuvir is an antiviral that inhibits the NS5B polymerase enzyme, which is important for the replication of the hepatitis C virus genome. Sofosbuvir is often used in combination with other antivirals to treat HCV and cure the infection in many cases.
Indications for Sofosbuvir
● Chronic Hepatitis C: Sofosbuvir is used to treat chronic hepatitis C infection in adults and children, often in combination with other antiviral medications.
Dosage and Administration
● For Hepatitis C: 400 mg daily, usually in combination with other antiviral medications like Ledipasvir or Ribavirin.
Side Effects of Sofosbuvir
● Common: Fatigue, headache, nausea, diarrhea.
● Serious: Liver problems, reactivation of hepatitis B virus in co-infected patients.
● Pregnancy Category: Category B (no evidence of harm in human studies).
Common Brands in India
● Resof
● Hepcinat
● Sofovir
●Sovihep
FAQ
What is Sofosbuvir used for?
How is Sofosbuvir taken?
Sofosbuvir is typically taken as a 400 mg tablet once a day, often in combination with other antiviral medications. It should be taken with food.