Non-Invasive Prenatal Testing (NIPT) is a blood test used to screen for certain genetic conditions in the fetus, such as Down syndrome (trisomy 21), trisomy 18, and trisomy 13. NIPT analyzes the small amounts of fetal DNA circulating in the mother’s blood.
Indications for NIPT Test:
● Advanced maternal age: Women over the age of 35 are at higher risk for genetic disorders and may be offered NIPT.
● Family history of genetic disorders: Couples with a family history of Down syndrome or other chromosomal abnormalities may choose NIPT for early detection.
● Positive results from other screenings: If earlier tests, such as the first trimester screening or ultrasound, suggest a risk for chromosomal abnormalities, NIPT can provide more detailed information.
How NIPT Works:
● A blood sample is taken from the mother, and fetal DNA is analyzed. NIPT uses advanced technology to assess chromosomal abnormalities if any in the fetal DNA.
Normal Range:
● Normal results indicate a low risk of chromosomal abnormalities.
Abnormal Test Significance:
● Positive results suggest a higher risk of genetic conditions like Down syndrome, trisomy 18, or trisomy 13.
Management Based on Results:
● For positive NIPT results: Further diagnostic testing like amniocentesis or chorionic villus sampling (CVS) may be recommended to confirm the findings.
● For negative results: No further genetic testing is necessary, but routine prenatal care should continue.
Price in India:
Approx. ₹12,000 – ₹25,000 for NIPT.
Frequently Asked Questions
Is NIPT 100% accurate?
While NIPT is highly accurate, it is a screening test, not a diagnostic one. Positive results should be followed up with diagnostic tests.
When should I get NIPT?
NIPT is typically done after 10 weeks of pregnancy.
Disclaimer: NIPT provides valuable screening information, but it cannot confirm the presence of genetic conditions. Diagnostic testing is required for confirmation.
How HealthPil Can Help:
HealthPil connects you with genetic counselors and obstetricians who can help interpret NIPT results and guide you through further testing or management based on the findings.