Inflammatory Markers – Understanding Inflammation in the Body
Inflammatory Markers are a group of blood tests that help detect inflammation in the body. Chronic inflammation is associated with several diseases, including autoimmune conditions, heart disease, and infectious diseases.
Indications for Inflammatory Markers Test:
● Chronic pain or swelling: Persistent pain or swelling may indicate an inflammatory process, commonly seen in rheumatoid arthritis or systemic lupus erythematosus (SLE).
● Fever of unknown origin: If doctors suspect an inflammatory or infectious cause.
● Monitoring chronic diseases: To assess disease activity in autoimmune diseases like rheumatoid arthritis or inflammatory bowel disease (IBD).
Common Inflammatory Markers Tested:
1. C-Reactive Protein (CRP): Elevated levels indicate acute or chronic inflammation.
2. Erythrocyte Sedimentation Rate (ESR): Measures how quickly red blood cells settle, which can increase in the presence of inflammation.
3. Ferritin: As discussed, elevated ferritin levels can also serve as an indicator of inflammation.
4. Procalcitonin (PCT): Elevated levels are associated with sepsis and bacterial infections.
Normal Range:
● CRP: Less than 10 mg/L.
● ESR: Men: 0–15 mm/hr; Women: 0–20 mm/hr.
● Procalcitonin: Less than 0.5 ng/mL.
Abnormal Test Significance:
● Elevated CRP and ESR: Suggest acute or chronic inflammation, often linked to autoimmune diseases, infections, or even heart disease.
● Elevated procalcitonin: Often indicates a bacterial infection or sepsis.
Management Based on Results:
● For inflammation: Treatment depends on the underlying cause. For autoimmune conditions, immunosuppressive drugs or biologic therapies may be required. For infections, antibiotics or antiviral medications are prescribed.
Price in India:
● Approx. ₹1,500 – ₹4,000 for inflammatory marker testing (including CRP, ESR, and procalcitonin).
FAQs
What causes inflammation in the body?
Inflammation can be caused by infections, autoimmune diseases, chronic conditions, or injuries.
How do I know if I need an inflammatory marker test?
If you have symptoms like chronic pain, swelling, or fever, or if you are managing a chronic disease like arthritis, this test is useful.
Can inflammation go unnoticed?
Yes, chronic low-grade inflammation may not always cause noticeable symptoms but can contribute to conditions like heart disease and diabetes.
Disclaimer:
Inflammatory markers are useful for diagnosing conditions related to inflammation, but the results should be interpreted by a healthcare provider who can consider other diagnostic tests and clinical symptoms.
How HealthPil Can Help:
HealthPil offers access to rheumatologists and general physicians who can help interpret your inflammatory markers test results and guide you through treatment options for autoimmune diseases, infections, and heart disease.