Lisinopril: The ACE Inhibitor for Blood Pressure and Heart Failure
What is Lisinopril?
Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor which is a go to drug to keep high blood pressure (hypertension) and heart failure under check. It blocks the transition of angiotensin I to angiotensin II, a substance that constricts blood vessel walls. Hence, Lisinopril helps to relax blood vessels, making it easier for the heart to pump blood.
How Lisinopril Works
Lisinopril prevents the formation of angiotensin II, which lowers the blood pressure and reduces the risk of stroke, kidney failure, and heart failure symptoms.
When to Use Lisinopril
● Hypertension: Lisinopril is used to lower blood pressure and prevent complications like stroke and kidney damage.
● Heart Failure: It helps to reduce the heart’s workload and prevent hospitalizations.
● Post-Heart Attack: Lisinopril is often prescribed after a heart attack to improve survival rates.
Dosage
● Adult Dose for Hypertension: Typically starts with 10 mg once daily, which may be increased depending on blood pressure levels.
● Adult Dose for Heart Failure: Doses usually start at 5 mg once daily, increasing as tolerated.
Side Effects
● Common Effects: Dizziness, headache, fatigue, and low blood pressure.
● Serious Adverse Effects: Angioedema (swelling of the face, lips, and throat), elevated potassium levels, and kidney dysfunction.
Common brands: Listril, Lipril.