Imipramine: An Antidepressant and Anti Anxiety medication
What is Imipramine?
Imipramine is a tricyclic antidepressant (TCA) used to treat major depressive disorder, anxiety disorders, and bedwetting in children. It works by increasing the levels of serotonin and norepinephrine in the brain.
How Imipramine Works
Imipramine inhibits the reuptake of serotonin and norepinephrine, two neurotransmitters that regulate mood and emotional well-being. This increases their levels in the brain, improving mood and helping manage anxiety and depressive symptoms.
When to Use Imipramine
● Depression: Used to treat major depressive disorder and dysthymia.
● Anxiety: Helps control generalized anxiety and panic attacks.
● Bedwetting: Used off-label for children with bedwetting (enuresis).
Dosage
● Adult Dose: 25-100 mg daily, typically taken in the evening. Maximum dose is 200 mg/day based on response and tolerability.
● Pediatric Dose: 1.5 mg/kg/day in 2-3 divided doses, maximum daily dose is 5 mg/kg/day, gradually increasing based on response. For bedwetting children the starting dose is 25 mg at bedtime and gradually increased to a maximum of 150 mg based on the response.
Side Effects
● Common Effects: Dry mouth, constipation, blurred vision, dizziness, and weight gain.
● Serious Adverse Effects: Cardiac arrhythmias, seizures, and suicidal thoughts—especially in young people.
Common Brands in India: Depsonil, Depsol.
FAQ
How long does it take for Imipramine to work?
Improvement is typically seen within 2-4 weeks, but full effects may take longer.
Can Imipramine cause weight gain?
Yes, weight gain is a known side effect due to its appetite-stimulating properties.
Is Imipramine safe for children?
It can be used in children for bedwetting, but regular monitoring is necessary for side effects.
Disclaimer
Imipramine should be used under careful supervision, as it may cause serious side effects like heart problems and suicidal thoughts. Always consult a healthcare provider before use.
How HealthPil Can Help
HealthPil connects you with psychiatrists and mental health specialists who can guide you through the safe use of Imipramine for depression, anxiety, or enuresis. With virtual consultations, we ensure that you receive comprehensive care, monitoring, and support throughout your treatment.
