Fentanyl: The Potent Opioid for Severe Pain
What is Fentanyl?
Fentanyl is a synthetic opioid used to treat severe pain, particularly in patients with cancer or after surgery. It is generally used as an adjunct to regional or general anaesthesia. It is much more potent than morphine, making it effective in controlling pain that doesn’t respond to other analgesics.
How Fentanyl Works
Fentanyl binds to opioid receptors in the brain, spinal cord, and other organs, altering the perception of pain and producing feelings of euphoria and relaxation.
When to Use Fentanyl
● Cancer Pain: Provides relief from severe, chronic cancer pain.
● Post-Surgical Pain: Used in patients recovering from major surgery.
● Pain Management in ICU: For critically ill patients.
Dosage
● Adult Dose: In cases of continuous infusion 0.7- 10 mcg/kg/hour. For breakthrough cancer pain initial dosage is 200 mcg. Maximum dosage is 1200 mcg/dose. Oral mucosal tablets are available as 200 mcg/tablet.
● Pediatric Dose: 0.5-2 mcg/kg/hour for pain relief in neonates. In infants and children it is generally 2-3 mcg/kg/hour.
Side Effects
● Respiratory depression, dizziness, constipation, sedation.
Common Brands in India: Sublimaze, Duragesic.
FAQ
Is Fentanyl safe for long-term use?
Fentanyl is prescribed for short-term use due to its high potential for addiction and overdose
Disclaimer
Fentanyl is a controlled substance. Always consult a healthcare provider before using it. HealthPil can help connect you to pain management specialists.
