Colchicine: Treatment for Gout and Familial Mediterranean Fever
Colchicine is an anti-inflammatory medication primarily used to treat acute gout attacks and familial Mediterranean fever (FMF). It works by reducing inflammation and preventing the formation of uric acid crystals in the joint space that causes pain in gout patients.
Common Indications of Colchicine
● Acute gout flares
● Familial Mediterranean fever (FMF)
● Pericarditis (off-label use)
Dosage and Administration
● Acute Gout Attack: 1.2 mg orally at the onset of a flare, followed by another 0.6 mg dose one hour afterward.
● Chronic Gout: 0.6 mg once or twice daily.
● FMF: 1.2-2.4 mg orally daily.
Colchicine is available in oral tablet form.
Adverse Effects of Colchicine
● Diarrhea
● Nausea and vomiting
● Abdominal pain
● Myopathy and neuropathy (with prolonged use)
Contraindications of Colchicine
● Severe renal or hepatic impairment
● Hypersensitivity to colchicine
Pregnancy, Liver, and Kidney Considerations
● Pregnancy: Colchicine is an FDA category C drug. Use only if necessary.
● Liver: Patients with liver impairment should use colchicine cautiously.
● Kidneys: Dose adjustments are required for patients with renal impairment.
How We Can Help
At HealthPil, our rheumatologists can provide personalized care for gout and other inflammatory conditions treated with Colchicine. Book an appointment.
Disclaimer
This content is for informational purposes only. Consult a healthcare provider before using any medication
