Montelukast: The Leukotriene Receptor Antagonist for Asthma and Allergies
What is Montelukast?
Montelukast is a leukotriene receptor antagonist used for the treatment and prophylaxis of asthma and allergic rhinitis (hay fever). It is also indicated in exercise induced bronchoconstriction in children above 6 years of age. It works by blocking the action of leukotrienes, chemicals in the body that cause inflammation, bronchoconstriction, and allergic reactions.
How Montelukast Works
Montelukast selectively blocks leukotriene receptors in the airways and blood vessels, which prevents the inflammatory response and helps relieve asthma symptoms and allergy symptoms like sneezing and nasal congestion.
When to Use Montelukast
● Asthma: Montelukast is used for preventive treatment of asthma in both adults and children.
● Allergic Rhinitis: It helps alleviate symptoms of seasonal allergies, such as nasal congestion, itching, and runny nose.
● Exercise-Induced Bronchoconstriction: It can be used to prevent asthma symptoms triggered by exercise.
Dosage
● Adult Dose: 10 mg once daily in the evening, 2 hours prior to exercise.
● Pediatric Dose: For children aged 6-14 years, 5 mg once daily, and for children aged 6 months-5 years, 4 mg once daily, Children above 15 years are given the usual adult dose.
Side Effects
● Common Effects: Headache, abdominal pain, and cough.
● Serious Adverse Effects: Mood changes, sleep disturbances, and churg-strauss syndrome (a rare condition causing inflammation of blood vessels).
Common Indian brands: Montair, Montek
